Non‐model organisms and unique approaches are needed for the future of evo‐devo
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Dynamics"
DOI: 10.1002/dvdy.71
Abstract: Over the past decade, we have seen a wonderful interconnectedness between the fields of developmental biology and evolutionary biology. Understanding how organisms achieve their uniqueness, be it morphological or mechanistic, is best understood with a… read more here.
Keywords: non model; model; model organisms; biology ... See more keywords
SNP Discovery from Single and Multiplex Genome Assemblies of Non-model Organisms.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7514-3_9
Abstract: Population genetic studies of non-model organisms often rely on initial ascertainment of genetic markers from a single individual or a small pool of individuals. This initial screening has been a significant barrier to beginning population… read more here.
Keywords: snp discovery; model; model organisms; genome ... See more keywords
Role of model organisms and nanocompounds in human health risk assessment
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Monitoring and Assessment"
DOI: 10.1007/s10661-021-09066-2
Abstract: Safeguarding the environment is one of the most serious modern challenges, as increasing amounts of chemical compounds are produced and released into the environment, causing a serious threat to the future health of the Earth… read more here.
Keywords: role model; risk; model organisms; health ... See more keywords
Habituation in high-throughput genetic model organisms as a tool to investigate the mechanisms of neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2020.107208
Abstract: Alterations in habituation, a highly conserved form of non-associative learning, are suspected to contribute to a range of the complex behavioural phenotypes present in multiple neurodevelopmental disorders. While progress has been made in understanding the… read more here.
Keywords: genetic model; habituation; model organisms; throughput genetic ... See more keywords
Proteomics in non-model organisms: a new analytical frontier.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.0c00448
Abstract: For the last century we have relied on model organisms to help understand fundamental biological processes. Now, with advancements in genome sequencing, assembly and annotation, non-model organisms may be studied with the same advanced bioanalytical… read more here.
Keywords: research; proteomics non; model; model organisms ... See more keywords
Autophagy as a promoter of longevity: insights from model organisms
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/s41580-018-0033-y
Abstract: Autophagy is a conserved process that catabolizes intracellular components to maintain energy homeostasis and to protect cells against stress. Autophagy has crucial roles during development and disease, and evidence accumulated over the past decade indicates… read more here.
Keywords: longevity; promoter longevity; longevity insights; autophagy promoter ... See more keywords
Developmental genetics with model organisms
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2122148119
Abstract: In Darwin’s and Mendel’s times, researchers investigated a wealth of organisms, chosen to solve particular problems for which they seemed especially well suited. Later, a focus on a few organisms, which are accessible to systematic… read more here.
Keywords: genetics model; model organisms; developmental genetics; model ... See more keywords
Diverse data supports the transition of filamentous fungal model organisms into the post-genomics era
Sign Up to like & getrecommendations! Published in 2017 at "Mycology"
DOI: 10.1080/21501203.2017.1281849
Abstract: ABSTRACT Filamentous fungi have been important as model organisms since the beginning of modern biological inquiry and have benefitted from open data since the earliest genetic maps were shared. From early origins in simple Mendelian… read more here.
Keywords: research; genetics; filamentous fungi; model ... See more keywords
Are model organisms representative for climate change research? Testing thermal tolerance in wild and laboratory zebrafish populations
Sign Up to like & getrecommendations! Published in 2019 at "Conservation Physiology"
DOI: 10.1093/conphys/coz036
Abstract: Despite long-term domestication to stable temperatures, laboratory-strain zebrafish have kept the same upper thermal tolerance as wild-caught zebrafish held under laboratory conditions. Wild zebrafish tested in India, however, had a lower thermal tolerance highlighting that… read more here.
Keywords: thermal tolerance; organisms representative; tolerance; representative climate ... See more keywords
DMKPs provide a generalizable strategy for studying genes required for reproduction or viability in non-traditional model organisms.
Sign Up to like & getrecommendations! Published in 2023 at "Genetics"
DOI: 10.1093/genetics/iyad057
Abstract: The advent of CRISPR/Cas9-mediated genome editing has expanded the range of animals amenable to targeted genetic analysis. This has accelerated research in animals not traditionally studied using molecular genetics. However, studying genes essential for reproduction… read more here.
Keywords: zpg; model organisms; studying genes; reproduction ... See more keywords
PertOrg 1.0: a comprehensive resource of multilevel alterations induced in model organisms by in vivo genetic perturbation
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac872
Abstract: Abstract Genetically modified organisms (GMOs) can be generated to model human genetic disease or plant disease resistance, and they have contributed to the exploration and understanding of gene function, physiology, disease onset and drug target… read more here.
Keywords: multilevel alterations; model organisms; pertorg; genetic perturbation ... See more keywords