KRAS drives immune evasion in a genetic model of pancreatic cancer
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-21736-w
Abstract: Immune evasion is a hallmark of KRAS-driven cancers, but the underlying causes remain unresolved. Here, we use a mouse model of pancreatic ductal adenocarcinoma to inactivate KRAS by CRISPR-mediated genome editing. We demonstrate that at… read more here.
Keywords: immune evasion; pancreatic cancer; model pancreatic; kras driven ... See more keywords
Current Pathology Model of Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14092321
Abstract: Simple Summary Pancreatic cancer is a very aggressive and lethal malignant neoplasm with overall 5-year survival rates below 10%. The field of pancreatic cancer research is rapidly evolving. Reports of newly revealed pathomechanisms of the… read more here.
Keywords: current pathology; pancreatic cancer; pathology; model pancreatic ... See more keywords