1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy
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DOI: 10.1080/14756366.2020.1748026
Abstract: Abstract There are numerous studies supporting the contribution of oxidative stress to the pathogenesis of epilepsy. Prolonged oxidative stress is associated with the overexpression of ATP-binding cassette transporters, which results in antiepileptic drugs resistance. During… read more here.
Keywords: epilepsy; pharmacoresistant epilepsy; ros scavenging; model pharmacoresistant ... See more keywords