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Published in 2022 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abg1787
Abstract: Gepotidacin is a first-in-class triazaacenaphthylene antibacterial agent that selectively inhibits bacterial DNA gyrase and topoisomerase IV through a unique binding mode and has the potential to treat a number of bacterial diseases. Development of this…
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Keywords:
pestis;
pneumonic plague;
plague;
model pneumonic ... See more keywords