Increases in dendritic spine density in BLA without metabolic changes in a rodent model of PTSD
Sign Up to like & getrecommendations! Published in 2019 at "Brain Structure and Function"
DOI: 10.1007/s00429-019-01943-4
Abstract: Imaging studies have shown abnormal amygdala function in patients with posttraumatic stress disorder (PTSD). In addition, alterations in synaptic plasticity have been associated with psychiatric disorders and previous reports have indicated alterations in the amygdala… read more here.
Keywords: density bla; model ptsd; dendritic spine; bla ... See more keywords
Blockade of muscarinic receptors impairs reconsolidation of older fear memory by decreasing cholinergic neurotransmission: A study in rat model of PTSD.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118014
Abstract: The age and strength of fear memory are two potential parameters that can be influenced by the impairing effects of pharmacological agents on reconsolidation of fear memory. In reconsolidation, stored information is rendered labile again… read more here.
Keywords: reconsolidation; memory; model ptsd; fear memory ... See more keywords
Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD
Sign Up to like & getrecommendations! Published in 2018 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2018.01.026
Abstract: ABSTRACT Posttraumatic stress disorder (PTSD) is a debilitating condition highly comorbid with depression. The endocannabinoid (eCB) system and brain‐derived neurotrophic factor (BDNF) are suggestively involved in both disorders. We examined whether cannabinoids can prevent the… read more here.
Keywords: model ptsd; depressive like; like symptoms; cannabinoids prevent ... See more keywords