Articles with "model ras" as a keyword



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A model for RAS mutation patterns in cancers: finding the sweet spot

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Published in 2018 at "Nature Reviews Cancer"

DOI: 10.1038/s41568-018-0076-6

Abstract: The three RAS genes — HRAS, NRAS and KRAS — are collectively mutated in one-third of human cancers, where they act as prototypic oncogenes. Interestingly, there are rather distinct patterns to RAS mutations; the isoform… read more here.

Keywords: ras mutation; model ras; mutation patterns; sweet spot ... See more keywords