Antiapoptosis effect of ZiShen prescription to increase learning and memory abilities of compound Alzheimer's disease model rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28399
Abstract: Alzheimer's disease (AD) is a neurodegenerative disease characterized progressive memory loss and cognitive impairment. In previous studies, the activities of extracts of Chinese medicinal herbs to treat brain function disorders caused by AD have already… read more here.
Keywords: zishen prescription; model rats; learning memory; prescription ... See more keywords
Age-related biochemical dysfunction in 6-OHDA model rats subject to induced- endurance exercise.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of gerontology and geriatrics"
DOI: 10.1016/j.archger.2021.104554
Abstract: Exercise can alleviate the disorders considered as the normal consequences of aging. Whether or not the treadmill endurance training affects the biochemical markers in the Parkinson's disease model rats after the 6-hydroxydopamine (6-OHDA) injection is… read more here.
Keywords: ohda; model rats; exercise; endurance exercise ... See more keywords
Anti-hemorrhoidal activity of Lian-Zhi-San, a traditional Chinese medicine, in an experimental hemorrhoidal model in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of integrative medicine"
DOI: 10.1016/j.joim.2020.09.006
Abstract: OBJECTIVE Hemorrhoidal disease (HD) is the most common proctological disease, with an estimated prevalence rate of 4.4%, and a peak in individuals between 45 and 65 years of age. This study was done to evaluate whether… read more here.
Keywords: medicine; lian zhi; anti hemorrhoidal; zhi san ... See more keywords
Telmisartan neuroprotective effects in 3-nitropropionic acid Huntington's disease model in rats: Cross talk between PPAR-γ and PI3K/Akt/GSK-3β pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.1016/j.lfs.2022.120480
Abstract: Huntington's disease (HD) is an inherited devastating neurodegenerative disorder with disabling motor and cognitive derangements that hinder the patients from performing their daily activities. AIMS The present study was carried out to investigate telmisartan-induced neuroprotection… read more here.
Keywords: akt gsk; huntington disease; neuroprotective effects; model rats ... See more keywords
MicroRNA-140 silencing represses the incidence of Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.135674
Abstract: Alzheimer's disease (AD) is a neurodegenerative condition leading to severe disability from progressive impairments in cognitive functions including memory and learning. Non-coding microRNAs (miRNAs or miRs) have been linked to the pathogenesis of AD. The… read more here.
Keywords: alzheimer disease; mir; 140 silencing; model rats ... See more keywords
Etidronate–zinc Complex Ameliorated Cognitive and Synaptic Plasticity Impairments in 2-Vessel Occlusion Model Rats by Reducing Neuroinflammation
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.08.022
Abstract: As one of the bisphosphonate derivatives, etidronate has proved to be beneficial to spatial learning and memory deficits caused by two-vessel occlusion (2-VO). In this study, the novel drug etidronate-zinc complex (Eti-Zn) was used to… read more here.
Keywords: synaptic plasticity; model rats; model; vessel occlusion ... See more keywords
A silk peptide fraction restores cognitive function in AF64A‐induced Alzheimer disease model rats by increasing expression of choline acetyltransferase gene
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2016.11.008
Abstract: Abstract This study investigated the effects of a silk peptide fraction obtained by incubating silk proteins with Protease N and Neutrase (SP‐NN) on cognitive dysfunction of Alzheimer disease model rats. In order to elucidate underlying… read more here.
Keywords: disease model; alzheimer disease; model rats; expression ... See more keywords
Characterization of an i.p. D-galactose-induced cataract model in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2020.106891
Abstract: Cataracts have been identified as a main cause of global visual impairment and blindness; in addition, diabetic and aging cataracts are the most common types. The aim of this project was to develop a suitable… read more here.
Keywords: characterization galactose; induced cataract; model; cataract model ... See more keywords
Glucocorticoid receptors participate in epilepsy in FCDII patients and MP model rats: A potential therapeutic target for epilepsy in patients with focal cortical dysplasia II (FCDII)
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2022.2032650
Abstract: ABSTRACT Background Glucocorticoid receptors (GRs) and mineralocorticoid receptors (MRs) are involved in neuronal excitability, neurogenesis, and neuroinflammation. However, the roles of GRs and MRs in epilepsy in focal cortical dysplasia II (FCDII) have not been… read more here.
Keywords: focal cortical; model rats; fcdii patients; glucocorticoid receptors ... See more keywords
Etidronate rescues cognitive deficits through improving synaptic transmission and suppressing apoptosis in 2‐vessel occlusion model rats
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.13904
Abstract: Vascular dementia is a neurodegenerative disorder caused by the reduction of cerebral blood flow. It shows a progressive cognitive impairment. In our previous study, we found that etidronate (ET) showed neuroprotective effects against glutamate‐injured PC12… read more here.
Keywords: apoptosis; model rats; model; 2vo rats ... See more keywords
Effect of Dihuang Yinzi on Inflammatory Response in Cerebral Ischemia-Reperfusion Model Rats by Regulating Gut Microbiota
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/3768880
Abstract: Dihuang Yinzi, as a classical Chinese medicine prescription, plays an important role for the treatment of ischemic stroke. Gut microbiota play a functional role for the expression of proinflammatory cytokines and anti-inflammatory cytokines, which further… read more here.
Keywords: model rats; brain; gut microbiota; dihuang yinzi ... See more keywords