Abstract 5830: A first-of-its-kind model that reconstitutes targeted drug-induced cellular transdifferentiation
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DOI: 10.1158/1538-7445.am2024-5830
Abstract: Introduction: Lung tumors treated with targeted therapies ultimately relapse due to intra-genic resistance mutations, bypass pathway activation, or cellular lineage changes. Newer precision therapies have higher selectivity and potency against both resistant and activating gene… read more here.
Keywords: first kind; model reconstitutes; transdifferentiation; drug ... See more keywords