A suppressor of dioxygenase inhibition in a yeast model of SDH deficiency.
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DOI: 10.1530/erc-21-0349
Abstract: A fascinating class of familial paraganglioma (PGL) neuroendocrine tumors is driven by loss of the tricarboxylic acid (TCA) cycle enzyme succinate dehydrogenase (SDH) resulting in succinate accumulation as an oncometabolite, and other metabolic derangements. Here… read more here.
Keywords: dioxygenase inhibition; yeast model; yeast; model ... See more keywords