Hypothalamic Monoaminergic Pathology in a Neurodevelopmental Rat Model Showing Prenatal 5-Bromo-2′-Deoxyuridine Treatment-Induced Hyperactivity and Hyporeproductivity
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DOI: 10.1159/000504552
Abstract: Objective: Prenatal treatment of rats with 5-bromo-2′-deoxyuridine (BrdU) is a neurodevelopmental model showing hyperactivity and impaired sexual activity. Human neurodevelopmental disorders, such as autism, exhibit sex-related pathology, but sex-related neurodevelopment has not been fully investigated… read more here.
Keywords: bromo deoxyuridine; model showing; treatment; pathology ... See more keywords