The oral ferroportin inhibitor vamifeport improves hemodynamics in a mouse model of sickle cell disease
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DOI: 10.1182/blood.2021014716
Abstract: Nyffenegger and colleagues report that blocking ferriportin with vamifeport reduces hemolysis in a murine model of sickle cell disease (SCD). Vamifeport reduces intracellular iron and induces iron-limited hematopoiesis. Since a small decrease in the intracellular… read more here.
Keywords: cell disease; vamifeport; sickle cell; hemodynamics ... See more keywords