Engineered Microsystems for Spheroid and Organoid Studies.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202001284
Abstract: 3D in vitro model systems such as spheroids and organoids provide an opportunity to extend the physiological understanding using recapitulated tissues that mimic physiological characteristics of in vivo microenvironments. Unlike 2D systems, 3D in vitro… read more here.
Keywords: microengineering techniques; vitro model; model systems; microsystems spheroid ... See more keywords
Evaluation of advances in cortical development using model systems
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22879
Abstract: Compared with that of even the closest primates, the human cortex displays a high degree of specialization and expansion that largely emerges developmentally. Although decades of research in the mouse and other model systems has… read more here.
Keywords: advances cortical; model systems; cortical development; evaluation advances ... See more keywords
Antioxidant and chelating capacity of Maillard reaction products in amino acid-sugar model systems: applications for food processing.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.8206
Abstract: BACKGROUND Maillard reaction products (MRP) have gained increasing interest owing to their both positive and negative effects on human health. Aqueous amino acid-sugar model systems were studied in order to evaluate the antioxidant and chelating… read more here.
Keywords: processing; capacity; model systems; model ... See more keywords
Nanoplastic Toxicity: Insights and Challenges from Experimental Model Systems.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202201680
Abstract: Nanoplastic particles (NPs) can be produced or derived from the degradation of several daily used products and can therefore be found in the air, water, and food. Every day, these microscopic particles are confronted by… read more here.
Keywords: model systems; insights challenges; toxicity; toxicity insights ... See more keywords
A protein-centric view of in vitro biological model systems for Schizophrenia.
Sign Up to like & getrecommendations! Published in 2021 at "Stem cells"
DOI: 10.1002/stem.3447
Abstract: Schizophrenia (SCZ) is a severe brain disorder, characterized by psychotic, negative and cognitive symptoms, affecting 1% of the population worldwide. The precise aetiology of SCZ is still unknown; however, SCZ has a high heritability, and… read more here.
Keywords: model systems; pathology; protein centric; brain ... See more keywords
Translational Model Systems for Complex Sodium Channel Pathophysiology in Pain.
Sign Up to like & getrecommendations! Published in 2018 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2017_91
Abstract: Chronic pain patients are often left with insufficient treatment as the pathophysiology especially of neuropathic pain remains enigmatic. Recently, genetic variations in the genes of the voltage-gated sodium channels (Navs) were linked to inherited neuropathic… read more here.
Keywords: model systems; sodium; pathophysiology; neuropathic pain ... See more keywords
Human placenta and trophoblast development: key molecular mechanisms and model systems
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03104-6
Abstract: Abnormal placentation is considered as an underlying cause of various pregnancy complications such as miscarriage, preeclampsia and intrauterine growth restriction, the latter increasing the risk for the development of severe disorders in later life such… read more here.
Keywords: model systems; human placenta; placenta trophoblast; trophoblast ... See more keywords
Model systems for studying polyphosphate biology: a focus on microorganisms.
Sign Up to like & getrecommendations! Published in 2021 at "Current genetics"
DOI: 10.1007/s00294-020-01148-x
Abstract: Polyphosphates (polyP) are polymers of inorganic phosphates joined by high-energy bonds to form long chains. These chains are present in all forms of life but were once disregarded as 'molecular fossils'. PolyP has gained attention… read more here.
Keywords: model systems; studying polyphosphate; systems studying; polyphosphate biology ... See more keywords
Representing heterogeneity in structural relationships among multiple choice variables using a latent segmentation approach
Sign Up to like & getrecommendations! Published in 2018 at "Transportation"
DOI: 10.1007/s11116-018-9882-7
Abstract: Travel model systems often adopt a single decision structure that links several activity-travel choices together. The single decision structure is then used to predict activity-travel choices, with those downstream in the decision-making chain influenced by… read more here.
Keywords: decision; activity travel; model systems; choice ... See more keywords
Chapter model systems in heterogeneous catalysis at the atomic level: a personal view
Sign Up to like & getrecommendations! Published in 2020 at "Science China Chemistry"
DOI: 10.1007/s11426-019-9671-0
Abstract: The review presents an overview of studies in the surface science of oxide and related surfaces with an emphasis of the studies performed in the authors’ group. Novel instruments and technique developments, as well as… read more here.
Keywords: atomic level; heterogeneous catalysis; catalysis atomic; model systems ... See more keywords
Exploring amyloid oligomers with peptide model systems.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2021.05.004
Abstract: The assembly of amyloidogenic peptides and proteins, such as the β-amyloid peptide, α-synuclein, huntingtin, tau, and islet amyloid polypeptide, into amyloid fibrils and oligomers is directly linked to amyloid diseases, such as Alzheimer's, Parkinson's, and… read more here.
Keywords: peptide model; peptides proteins; model systems; amyloidogenic peptides ... See more keywords