Hollow-fibre system model of tuberculosis reproducibility and performance specifications for best practice in drug and combination therapy development
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkad029
Abstract: Abstract Background The hollow-fibre system model of tuberculosis (HFS-TB) has been endorsed by regulators; however, application of HFS-TB requires a thorough understanding of intra- and inter-team variability, statistical power and quality controls. Methods Three teams… read more here.
Keywords: tuberculosis; fibre system; hollow fibre; system model ... See more keywords
Updating age-specific contact structures to match evolving demography in a dynamic mathematical model of tuberculosis vaccination
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1010002
Abstract: We investigated the effects of updating age-specific social contact matrices to match evolving demography on vaccine impact estimates. We used a dynamic transmission model of tuberculosis in India as a case study. We modelled four… read more here.
Keywords: demography; model tuberculosis; contact; age ... See more keywords