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Published in 2018 at "Soft matter"
DOI: 10.1039/c8sm00844b
Abstract: Interstitial flow in tumors is a key mechanism leading to cancer metastasis. Tumor growth is accompanied by the development of a leaky vasculature, which increases intratumoral pressure and generates an outward interstitial flow. This flow…
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Keywords:
interstitial flow;
model tumor;
pressure;
tumor ... See more keywords
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Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13187
Abstract: Computational modeling of biological systems is a powerful tool to clarify diverse processes contributing to cancer. The aim is to clarify the complex biochemical and mechanical interactions between cells, the relevance of intracellular signaling pathways…
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Keywords:
cell based;
tumor growth;
multiscale cell;
based model ... See more keywords
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Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.00287
Abstract: Anakoinosis is a new cancer treatment paradigm that posits a key role for communicative reprogramming within tumor systems. To date no mathematical or computational models of anakoinosis have been developed. Here we outline the NEATG_A…
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Keywords:
computational model;
tumor;
model tumor;
growth anakoinosis ... See more keywords