Toxoplasma gondii as a Model of In Vivo Host-Parasite Interactions.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9167-9_21
Abstract: Toxoplasma gondii is an intracellular, apicomplexan parasite of great importance in both human and animal health. Current research has identified a variety of important and necessary factors specific to the parasite that enable it to… read more here.
Keywords: host parasite; model; gondii model; model vivo ... See more keywords
A transgenic zebrafish model for in vivo long-term imaging of retinotectal synaptogenesis
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DOI: 10.1038/s41598-018-32409-y
Abstract: The retinotectal synapse in larval zebrafish, combined with live time-lapse imaging, provides an advantageous model for study of the development and remodelling of central synapses in vivo. In previous studies, these synapses were labelled by… read more here.
Keywords: synaptogenesis; zebrafish model; model vivo; stable lines ... See more keywords
A genetic model for in vivo proximity labelling of the mammalian secretome
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DOI: 10.1098/rsob.220149
Abstract: Organ functions are highly specialized and interdependent. Secreted factors regulate organ development and mediate homeostasis through serum trafficking and inter-organ communication. Enzyme-catalyzed proximity labeling enables the identification of proteins within a specific cellular compartment. Here,… read more here.
Keywords: genetic model; vivo proximity; proximity labelling; proximity ... See more keywords
PDX-derived organoids model in vivo drug response and secrete biomarkers
Sign Up to like & getrecommendations! Published in 2020 at "JCI Insight"
DOI: 10.1172/jci.insight.135544
Abstract: Patient-derived organoid models are proving to be a powerful platform for both basic and translational studies. Here we conduct a methodical analysis of pancreatic ductal adenocarcinoma (PDAC) tumor organoid drug response in paired patient-derived xenograft… read more here.
Keywords: response; pdx derived; drug response; drug ... See more keywords