Mouse models in modeling aging and cancer
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2019.03.002
Abstract: ABSTRACT Mouse models have been widely used in the research of human diseases. Aging, just as cancer, is influenced by the interaction of various genetic and environmental factors. Currently, aging could be induced by many… read more here.
Keywords: cancer mouse; mouse models; modeling aging; cancer ... See more keywords
Modeling aging and its impact on cellular function and organismal behavior
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2021.111577
Abstract: Aging is a complex phenomenon of functional decay in a biological organism. Although the effects of aging are readily recognizable in a wide range of organisms, the cause(s) of aging are ill defined and poorly… read more here.
Keywords: aging impact; modeling aging; biology; computational biology ... See more keywords
Organoids: An Emerging Tool to Study Aging Signature across Human Tissues. Modeling Aging with Patient-Derived Organoids
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221910547
Abstract: The biology of aging is focused on the identification of novel pathways that regulate the underlying processes of aging to develop interventions aimed at delaying the onset and progression of chronic diseases to extend lifespan.… read more here.
Keywords: derived organoids; modeling aging; aging patient; biology ... See more keywords
Large data and Bayesian modeling—aging curves of NBA players
Sign Up to like & getrecommendations! Published in 2019 at "Behavior Research Methods"
DOI: 10.3758/s13428-018-1183-8
Abstract: Researchers interested in changes that occur as people age are faced with a number of methodological problems, starting with the immense time scale they are trying to capture, which renders laboratory experiments useless and longitudinal… read more here.
Keywords: modeling aging; large data; bayesian modeling; data bayesian ... See more keywords