Mechanistic modeling of cation exchange chromatography scale-up considering packing inhomogeneities.
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DOI: 10.1002/jssc.202300031
Abstract: In process development and characterization, the scale-up of chromatographic steps is a crucial part and brings a number of challenges. Usually, scale-down models are used to represent the process step, and constant column properties are… read more here.
Keywords: scale; exchange chromatography; mechanistic modeling; cation exchange ... See more keywords