Modeling clinical outcomes in radiotherapy: NTCP, TCP and the "TECs".
Sign Up to like & getrecommendations! Published in 2023 at "Medical physics"
DOI: 10.1002/mp.16274
Abstract: Radiation therapy is a double-edged sword which damages both tumor and normal cells. Achieving treatments with high tumor control probability (TCP) yet low normal tissue complication probability (NTCP) is often a struggle because we rarely… read more here.
Keywords: clinical outcomes; effects clinic; outcomes radiotherapy; normal tissue ... See more keywords
Abstract C096: Modeling the clinical paradigm of lisavanbulin (BAL101553) deployment in patient-derived xenografts (PDX) of glioblastoma (GBM)
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-19-c096
Abstract: Lisavanbulin (LIS; BAL101553) is the prodrug of BAL27862, a microtubule-binding, tumor checkpoint controller and potential radiosensitizer. These studies evaluated optimal integration of LIS with standard of care radiation therapy (RT) and/or temozolomide (TMZ) using GBM… read more here.
Keywords: bal101553; lisavanbulin; modeling clinical; c096 ... See more keywords
Ontological Modeling of Clinical Study Forms.
Sign Up to like & getrecommendations! Published in 2023 at "Studies in health technology and informatics"
DOI: 10.3233/shti230253
Abstract: The use of eCRFs is now commonplace in clinical research studies. We propose here an ontological model of these forms allowing to describe them, to express their granularity and to link them to the relevant… read more here.
Keywords: ontological modeling; clinical study; study forms; modeling clinical ... See more keywords