Pharmacophore modeling coupled with molecular dynamic simulation approach to identify new leads for meprin-β metalloprotease
Sign Up to like & getrecommendations! Published in 2019 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2019.04.014
Abstract: Human meprin beta metalloprotease, a small subgroup of the astacin family, is a potent drug target for the treatment of several disorders such as fibrosis, neurodegenerative disease in particular Alzheimer and inflammatory bowel diseases. In… read more here.
Keywords: modeling coupled; metalloprotease; pharmacophore modeling; molecular dynamic ... See more keywords
Modeling the coupled dynamics of an asteroid with surface boulder motion
Sign Up to like & getrecommendations! Published in 2019 at "Icarus"
DOI: 10.1016/j.icarus.2019.05.038
Abstract: Abstract A new model is presented to investigate the interaction between the asteroid's 6-degrees-of-freedom dynamics and the state of boulders on its surface. The model considers boulder motion on the surface of the asteroid as… read more here.
Keywords: boulder motion; model; modeling coupled; surface ... See more keywords
Challenges and opportunities for modeling coupled human and natural systems
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DOI: 10.1093/nsr/nwad054
Abstract: With the growing recognition of coupled human and natural systems (CHANS), modeling CHANS with two-way feedbacks has become a frontier research area and a critical tool to achieve sustainability. The challenges in CHANS modeling and… read more here.
Keywords: opportunities modeling; human natural; natural systems; coupled human ... See more keywords
Modeling Coupled Heat and Mass Transfer in Peristaltic Cylindrical Flow of Robertson-Stiff Fluid
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DOI: 10.1142/s1758825119500923
Abstract: The Robertson–Stiff fluid (RS) is a yield-pseudo-plastic model which has been used to describe the rheological properties of drilling fluids, cement slurries and bentonite suspensions. Experimental... read more here.
Keywords: modeling coupled; robertson stiff; stiff fluid; heat mass ... See more keywords
Advances in Numerical Modeling of Coupled CFD Problems
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Marine Science and Engineering"
DOI: 10.3390/jmse11050978
Abstract: The development and application of numerical models to the simulation of coupled CFD problems has been the focus of research in various areas of science and engineering since the first decade of the 21st century… read more here.
Keywords: numerical modeling; coupled cfd; advances numerical; cfd problems ... See more keywords