Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice
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DOI: 10.1126/sciadv.ade0059
Abstract: CRISPR-Cas9 has been used successfully to introduce indels in somatic cells of rodents; however, precise editing of single nucleotides has been hampered by limitations of flexibility and efficiency. Here, we report technological modifications to the… read more here.
Keywords: crispr cas9; efficient cancer; modeling crispr; cancer modeling ... See more keywords