Organoids for Modeling Genetic Diseases.
Sign Up to like & getrecommendations! Published in 2018 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2017.12.006
Abstract: In less than a decade, organoid systems have emerged as an innovative and valid in vitro method to mimic in vivo pathophysiology. Organoids are 3D structures constituted by multiple organ-specific cell types that self-organize and… read more here.
Keywords: medicine; organoids modeling; modeling genetic; biology ... See more keywords
New conservation viewpoints when plants are viewed at one level higher. Integration of phylogeographic structure, niche modeling and genetic diversity in conservation planning of W Mediterranean larkspurs
Sign Up to like & getrecommendations! Published in 2019 at "Global Ecology and Conservation"
DOI: 10.1016/j.gecco.2019.e00580
Abstract: Abstract Protection and management of closely related endangered species and subspecies at a very narrow regional scale is the origin of multiple dysfunctional conservation decisions. These include artificially increased IUCN risk assessment categories and derived… read more here.
Keywords: genetic diversity; conservation planning; mediterranean larkspurs; niche modeling ... See more keywords
Modeling genetic platelet disorders with human pluripotent stem cells: mega-progress but wanting more on our plate(let)
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000671
Abstract: Purpose of review Megakaryocytes are rare hematopoietic cells that play an instrumental role in hemostasis, and other important biological processes such as immunity and wound healing. With the advent of cell reprogramming technologies and advances… read more here.
Keywords: pluripotent stem; platelet disorders; genetic platelet; platelet ... See more keywords
The power of geohistorical boundaries for modeling the genetic background of human populations: The case of the rural catalan Pyrenees
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1100440
Abstract: The genetic variation of the European population at a macro-geographic scale follows genetic gradients which reflect main migration events. However, less is known about factors affecting mating choices at a micro-geographic scale. In this study… read more here.
Keywords: power geohistorical; catalan pyrenees; modeling genetic; geohistorical boundaries ... See more keywords