2D- and 3D-QSAR Modeling of Imidazole-Based Glutaminyl Cyclase Inhibitors.
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DOI: 10.2174/1573409915666190918150136
Abstract: BACKGROUND Glutaminyl cyclase (QC) is a novel target in the battle against Alzheimer's disease, a highly prevalent neurodegenerative disorder. QC inhibitors have the potential to be developed as therapeutically useful anti-Alzheimer's disease agents. METHODS Linear… read more here.
Keywords: glutaminyl cyclase; alzheimer disease; imidazole based; qsar modeling ... See more keywords