Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas.
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DOI: 10.1016/j.celrep.2022.110385
Abstract: Plexiform neurofibromas (pNFs) are developmental tumors that appear in neurofibromatosis type 1 individuals, constituting a major source of morbidity and potentially transforming into a highly metastatic sarcoma (MPNST). pNFs arise after NF1 inactivation in a… read more here.
Keywords: like tumors; ipsc derived; ipsc; modeling ipsc ... See more keywords