Biphasic Modeling of Mitochondrial Metabolism Dysregulation during Aging.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2017.06.005
Abstract: Organismal aging is classically viewed as a gradual decline of cellular functions and a systemic deterioration of tissues that leads to an increased mortality rate in older individuals. According to the prevailing theory, aging is… read more here.
Keywords: modeling mitochondrial; activity; biphasic modeling; mitochondrial metabolism ... See more keywords
Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.800529
Abstract: Around one third of patients with mitochondrial disorders develop a kind of cardiomyopathy. In these cases, severity is quite variable ranging from asymptomatic status to severe manifestations including heart failure, arrhythmias, and sudden cardiac death.… read more here.
Keywords: modeling mitochondrial; pluripotent stem; disease; induced pluripotent ... See more keywords