Modeling neurodegeneration in chronic traumatic encephalopathy using gradient damage models
Sign Up to like & getrecommendations! Published in 2019 at "Computational Mechanics"
DOI: 10.1007/s00466-019-01717-z
Abstract: Chronic traumatic encephalopathy is a progressive neurodegenerative disorder that results from repetitive impacts to the head. Its distinguishing feature is an accumulation of abnormal tau proteins in characteristic regions within the brain. Histopathological studies reveal… read more here.
Keywords: neurodegeneration chronic; chronic traumatic; damage; traumatic encephalopathy ... See more keywords
Modeling neurodegeneration with mutant-tau organoids
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.07.031
Abstract: Greater understanding of the events preceding neurodegeneration is needed to design effective preventive and therapeutic strategies. In this issue of Cell, Bowles et al. (2021) report cerebral organoids that reveal early events in frontotemporal dementia pathogenesis… read more here.
Keywords: tau organoids; tau; neurodegeneration mutant; mutant tau ... See more keywords