Continuous Manufacturing and Molecular Modeling of Pharmaceutical Amorphous Solid Dispersions
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DOI: 10.1208/s12249-022-02408-4
Abstract: Amorphous solid dispersions enhance solubility and oral bioavailability of poorly water-soluble drugs. The escalating number of drugs with poor aqueous solubility, poor dissolution, and poor oral bioavailability is an unresolved problem that requires adequate interventions.… read more here.
Keywords: solid dispersions; continuous manufacturing; amorphous solid; molecular modeling ... See more keywords
Finite Element Analysis and Modeling in Pharmaceutical Tableting
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DOI: 10.3390/pharmaceutics14030673
Abstract: Finite element analysis (FEA) is a computational method providing numerical solutions and mathematical modeling of complex physical phenomena that evolve during compression tableting of pharmaceutical powders. Since the early 2000s, FEA has been utilized together… read more here.
Keywords: pharmaceutical tableting; element analysis; analysis modeling; finite element ... See more keywords