Polymer Modeling Predicts Chromosome Reorganization in Senescence
Sign Up to like & getrecommendations! Published in 2019 at "Cell Reports"
DOI: 10.1016/j.celrep.2019.08.045
Abstract: Summary Lamina-associated domains (LADs) cover a large part of the human genome and are thought to play a major role in shaping the nuclear architectural landscape. Here, we perform polymer simulations, microscopy, and mass spectrometry… read more here.
Keywords: chromosome reorganization; polymer modeling; senescence; reorganization senescence ... See more keywords
Data-driven computational modeling predicts “superhubs” play key role in epileptic dynamics
Sign Up to like & getrecommendations! Published in 2021 at "Neuron"
DOI: 10.1016/j.neuron.2021.07.024
Abstract: How individual neurons influence epileptic networks remains an open question. In this issue of Neuron, Hadjiabadi et al. (2021) use data-driven, computational models to predict the presence of "superhubs": highly connected neurons that drive network activity… read more here.
Keywords: computational modeling; predicts superhubs; data driven; modeling predicts ... See more keywords