Articles with "modeling rats" as a keyword



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Pharmacokinetic Characterization of Supinoxin and Its Physiologically Based Pharmacokinetic Modeling in Rats

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Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13030373

Abstract: Supinoxin is a novel anticancer drug candidate targeting the Y593 phospho-p68 RNA helicase, by exhibiting antiproliferative activity and/or suppression of tumor growth. This study aimed to characterize the in vitro and in vivo pharmacokinetics of… read more here.

Keywords: based pharmacokinetic; characterization supinoxin; physiologically based; supinoxin ... See more keywords