Modeling in-vivo protein-DNA binding by combining multiple-instance learning with a hybrid deep neural network
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-44966-x
Abstract: Modeling in-vivo protein-DNA binding is not only fundamental for further understanding of the regulatory mechanisms, but also a challenging task in computational biology. Deep-learning based methods have succeed in modeling in-vivo protein-DNA binding, but they… read more here.
Keywords: dna; vivo protein; protein dna; modeling vivo ... See more keywords
Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies
Sign Up to like & getrecommendations! Published in 2021 at "Oncoimmunology"
DOI: 10.1080/2162402x.2021.1959101
Abstract: ABSTRACT Adoptive transfer of tumor-infiltrating lymphocytes (TIL) elicits the regression of metastatic malignancies, yet a low proportion of patients achieve complete durable responses. The high incidence of relapse in these patients highlights the need to… read more here.
Keywords: tumor infiltrating; til; tumor; modeling vivo ... See more keywords
Fluorescence modeling of in vivo optical detection of Mycobacterium tuberculosis.
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical optics express"
DOI: 10.1364/boe.10.005445
Abstract: Tuberculosis is one of the deadliest infectious diseases worldwide. New tools to study pathogenesis and monitor subjects in pre-clinical studies to develop treatment regimens are critical for progress. We developed an improved optical system for… read more here.
Keywords: optical detection; detection; fluorescence modeling; vivo optical ... See more keywords