Articles with "modelling cyp2c19" as a keyword



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Physiologically‐based pharmacokinetic modelling of a CYP2C19 substrate, BMS‐823778, utilizing pharmacogenetic data

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Published in 2018 at "British Journal of Clinical Pharmacology"

DOI: 10.1111/bcp.13565

Abstract: Previous studies demonstrated direct correlation between CYP2C19 genotype and BMS‐823778 clearance in healthy volunteers. The objective of the present study was to develop a physiologically‐based pharmacokinetic (PBPK) model for BMS‐823778 and use the model to… read more here.

Keywords: based pharmacokinetic; pharmacokinetic modelling; bms 823778; physiologically based ... See more keywords