Thermodynamic Models for Assembly of Intrinsically Disordered Protein Hubs with Multiple Interaction Partners.
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DOI: 10.1021/jacs.1c00811
Abstract: Prevalent in diverse protein interactomes, intrinsically disordered proteins or regions (IDPs or IDRs) often drive assembly of higher-order macromolecular complexes, using multiple target-binding motifs. Such IDP hubs are suggested to process various cellular signals and… read more here.
Keywords: protein; hubs multiple; thermodynamic models; models assembly ... See more keywords