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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1311-5_25
Abstract: Asthma is a highly prevalent lung disease, characterized by airway dysfunction and chronic inflammation. Asthma occurs in both children and adults, but frequently originates in early life. Heterogeneous asthma phenotypes exist, but Th2 cells are…
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Keywords:
mouse models;
experimental mouse;
asthma analysis;
analysis cd4 ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8570-8_23
Abstract: Mouse models are critical for delineating the mechanisms that underlie asthma pathogenesis and developing new treatments. In this chapter we describe four different asthma models that offer unique benefits and allow investigators to answer distinct…
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Keywords:
mouse models;
biology;
mouse;
models asthma ... See more keywords
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Published in 2017 at "Journal of Asthma and Allergy"
DOI: 10.2147/jaa.s121092
Abstract: Clinical studies in asthma are not able to clear up all aspects of disease pathophysiology. Animal models have been developed to better understand these mechanisms and to evaluate both safety and efficacy of therapies before…
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Keywords:
utility limitations;
disease;
animal models;
asthma utility ... See more keywords