Structural models of the biological oxygen-evolving complex: achievements, insights, and challenges for biomimicry
Sign Up to like & getrecommendations! Published in 2017 at "Green Chemistry"
DOI: 10.1039/c7gc00425g
Abstract: The oxygen-evolving complex (OEC) in Photosystem II (PS-II) of oxygenic photosynthesis catalyzes the oxidation of water into dioxygen, protons and electrons, a reaction that underpins solar to chemical energy conversion in the biosphere. The inorganic… read more here.
Keywords: models biological; chemistry; structural models; oxygen evolving ... See more keywords
Comparing Petri net-based models of biological systems using Holmes
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DOI: 10.1093/bioinformatics/btac540
Abstract: MOTIVATION The first and necessary step in systems approach to study biological phenomana is building a formal model. One of the possibilities is to construct a model based on Petri nets. They have an intuitive… read more here.
Keywords: biological systems; models biological; net based; comparing petri ... See more keywords
Parameter estimation in models of biological oscillators: an automated regularised estimation approach
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-2630-y
Abstract: BackgroundDynamic modelling is a core element in the systems biology approach to understanding complex biosystems. Here, we consider the problem of parameter estimation in models of biological oscillators described by deterministic nonlinear differential equations. These… read more here.
Keywords: estimation; estimation models; models biological; parameter estimation ... See more keywords
Animal models in biological and biomedical research - experimental and ethical concerns.
Sign Up to like & getrecommendations! Published in 2019 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765201720170238
Abstract: Animal models have been used in experimental research to increase human knowledge and contribute to finding solutions to biological and biomedical questions. However, increased concern for the welfare of the animals used, and a growing… read more here.
Keywords: biomedical research; research; models biological; research experimental ... See more keywords
BioLQM: A Java Toolkit for the Manipulation and Conversion of Logical Qualitative Models of Biological Networks
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.01605
Abstract: Here we introduce bioLQM, a new Java software toolkit for the conversion, modification, and analysis of Logical Qualitative Models of biological regulatory networks. BioLQM provides core modeling operations as building blocks for the development of… read more here.
Keywords: logical qualitative; networks biolqm; models biological; analysis ... See more keywords
In Vitro Models of Biological Barriers for Nanomedical Research
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23168910
Abstract: Nanoconstructs developed for biomedical purposes must overcome diverse biological barriers before reaching the target where playing their therapeutic or diagnostic function. In vivo models are very complex and unsuitable to distinguish the roles plaid by… read more here.
Keywords: cell; vitro models; models biological; biological barriers ... See more keywords
Interaction of Oxicam Derivatives with the Artificial Models of Biological Membranes—Calorimetric and Fluorescence Spectroscopic Study
Sign Up to like & getrecommendations! Published in 2022 at "Membranes"
DOI: 10.3390/membranes12080791
Abstract: The modified 1,2-benzothiazine analogues designed as new drug candidates and discussed in this paper are oxicam derivatives. Oxicams are a class of non-steroidal anti-inflammatory drugs (NSAIDs). Their biological target is cyclooxygenase (COX), a membrane protein… read more here.
Keywords: interaction; artificial models; models biological; oxicam derivatives ... See more keywords
Symmetries in Dynamic Models of Biological Systems: Mathematical Foundations and Implications
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DOI: 10.3390/sym14030467
Abstract: Symmetries are ubiquitous in nature. Almost all organisms have some kind of “symmetry”, meaning that their shape does not change under some geometric transformation. This geometrical concept of symmetry is intuitive and easy to recognize.… read more here.
Keywords: symmetries dynamic; dynamic models; systems mathematical; biological systems ... See more keywords