Building Models of Brain Disorders with Three-Dimensional Organoids
Sign Up to like & getrecommendations! Published in 2018 at "Neuron"
DOI: 10.1016/j.neuron.2018.10.007
Abstract: Disorders of the nervous system are challenging to study and treat due to the relative inaccessibility of functional human brain tissue for research. Stem cell-derived 3D human brain organoids have the potential to recapitulate features… read more here.
Keywords: models brain; building models; disorders three; human brain ... See more keywords
Experimental animal models for brain abscess: a systematic review.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of neurosurgery"
DOI: 10.1080/02688697.2022.2160865
Abstract: BACKGROUND Brain abscess (BA) is a rare, but severe infection and experimental BA animal models may prove crucial for advances in treatment. This review describes the development of experimental BA models and the clinical advances… read more here.
Keywords: animal models; experimental animal; review; models brain ... See more keywords
Clinical Application of Machine Learning Models for Brain Imaging in Epilepsy: A Review
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.684825
Abstract: Epilepsy is a common neurological disorder characterized by recurrent and disabling seizures. An increasing number of clinical and experimental applications of machine learning (ML) methods for epilepsy and other neurological and psychiatric disorders are available.… read more here.
Keywords: epilepsy; machine learning; models brain; imaging epilepsy ... See more keywords
Prediction Models for Brain Distribution of Drugs Based on Biomimetic Chromatographic Data
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27123668
Abstract: The development of high-throughput approaches for the valid estimation of brain disposition is of great importance in the early drug screening of drug candidates. However, the complexity of brain tissue, which is protected by a… read more here.
Keywords: brain disposition; brain; prediction models; models brain ... See more keywords
Cognitive and Neurophysiological Models of Brain Asymmetry
Sign Up to like & getrecommendations! Published in 2022 at "Symmetry"
DOI: 10.3390/sym14050971
Abstract: Asymmetry is an inherent characteristic of brain organization in both humans and other vertebrate species, and is evident at the behavioral, neurophysiological, and structural levels. Brain asymmetry underlies the organization of several cognitive systems, such… read more here.
Keywords: theoretical models; cognitive neurophysiological; brain; models brain ... See more keywords