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Published in 2019 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a037077
Abstract: Metastasis, the dispersal of cancer cells from a primary tumor to secondary sites within the body, is the leading cause of cancer-related death. Animal models have been an indispensable tool to investigate the complex interactions…
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Keywords:
vivo models;
metastasis;
models cancer;
metastasis zebrafish ... See more keywords
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Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.5_suppl.1
Abstract: 1Background: The growing population of cancer survivors (15.5 million in the US) face myriad health issues that require health care attention. Cancer is increasingly viewed as a chronic illness that, once treated, requires systematic and…
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Keywords:
survivorship care;
models cancer;
cancer;
care ... See more keywords
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Published in 2018 at "Future oncology"
DOI: 10.2217/fon-2018-0028
Abstract: The CRISPR-Cas9, a part of the defence mechanism from bacteria, has rapidly become the simplest, fastest and the most precise genome-editing tool available. The therapeutic applications of CRISPR are boundless: correction of mutations in several…
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Keywords:
therapies experimental;
crispr cas9;
cas9 therapies;
models cancer ... See more keywords
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Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.01660
Abstract: The use of the Xenopus model system has provided diverse contributions to cancer research, not least because of the striking parallels between tumour pathogenesis and early embryo development. Cell cycle regulation, signalling pathways, and cell…
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Keywords:
xenopus;
xenopus models;
cancer expanding;
expanding oncologist ... See more keywords
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Published in 2017 at "Veterinary Sciences"
DOI: 10.3390/vetsci4020021
Abstract: Cancer-associated hypercalcemia (CAH) is a frequently-occurring paraneoplastic syndrome that contributes to substantial patient morbidity and occurs in both humans and animals. Patients with CAH are often characterized by markedly elevated serum calcium concentrations that result…
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Keywords:
hypercalcemia;
associated hypercalcemia;
models cancer;
cancer associated ... See more keywords