Delay differential equation-based models of cardiac tissue: Efficient implementation and effects on spiral-wave dynamics.
Sign Up to like & getrecommendations! Published in 2019 at "Chaos"
DOI: 10.1063/1.5128240
Abstract: Delay differential equations (DDEs) recently have been used in models of cardiac electrophysiology, particularly in studies focusing on electrical alternans, instabilities, and chaos. A number of processes within cardiac cells involve delays, and DDEs can… read more here.
Keywords: spiral wave; cardiac tissue; models cardiac; tissue ... See more keywords
Preclinical rodent models of cardiac fibrosis.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of pharmacology"
DOI: 10.1111/bph.15450
Abstract: Cardiac fibrosis (scarring), characterised by an increased deposition of extracellular matrix (ECM) proteins, is a hallmark of most types of cardiovascular disease and plays an essential role in heart failure progression. Inhibition of cardiac fibrosis… read more here.
Keywords: heart; fibrosis; cardiac fibrosis; models cardiac ... See more keywords
Zebrafish Models of Cardiac Disease: From Fortuitous Mutants to Precision Medicine
Sign Up to like & getrecommendations! Published in 2022 at "Circulation Research"
DOI: 10.1161/circresaha.122.320396
Abstract: Heart disease is the leading cause of death worldwide. Despite decades of research, most heart pathologies have limited treatments, and often the only curative approach is heart transplantation. Thus, there is an urgent need to… read more here.
Keywords: cardiac disease; disease; cardiac diseases; models cardiac ... See more keywords
Validation and Trustworthiness of Multiscale Models of Cardiac Electrophysiology
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DOI: 10.3389/fphys.2018.00106
Abstract: Computational models of cardiac electrophysiology have a long history in basic science applications and device design and evaluation, but have significant potential for clinical applications in all areas of cardiovascular medicine, including functional imaging and… read more here.
Keywords: cep; validation; credibility; models cardiac ... See more keywords