Structured models of cell migration incorporating molecular binding processes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Mathematical Biology"
DOI: 10.1007/s00285-017-1120-y
Abstract: The dynamic interplay between collective cell movement and the various molecules involved in the accompanying cell signalling mechanisms plays a crucial role in many biological processes including normal tissue development and pathological scenarios such as… read more here.
Keywords: models cell; structured models; cell migration; molecular binding ... See more keywords
Inference of dynamic macroscopic models of cell metabolism based on elementary flux modes analysis
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2019.107325
Abstract: Abstract This study aims at providing a methodology based on both data- and knowledge-driven approaches to build dynamic macroscopic models of cell cultures. This methodology proceeds in three steps. A principal component analysis is first… read more here.
Keywords: elementary flux; methodology; models cell; flux modes ... See more keywords
Preclinical studies and clinical trials on mesenchymal stem cell therapy for knee osteoarthritis: A systematic review on models and cell doses
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.14306
Abstract: To provide a systematic analysis of the study design in knee osteoarthritis (OA) preclinical studies, focusing on the characteristics of animal models and cell doses, and to compare these to the characteristics of clinical trials… read more here.
Keywords: clinical trials; models cell; mesenchymal stem; cell doses ... See more keywords
Dynamical analysis for delayed virus infection models with cell-to-cell transmission and density-dependent diffusion
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Biomathematics"
DOI: 10.1142/s1793524520500606
Abstract: In this paper, certain delayed virus dynamical models with cell-to-cell infection and density-dependent diffusion are investigated. For the viral model with a single strain, we have proved the well... read more here.
Keywords: density dependent; models cell; dependent diffusion; delayed virus ... See more keywords