Using retinal function to define ischemic exclusion criteria for animal models of glaucoma.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108354
Abstract: Most animal models of glaucoma rely on induction of ocular hypertension (OHT), yet such models can suffer from high IOPs leading to undesirable retinal ischemia. Thus, animals with IOPs exceeding a threshold (e.g. > 60 mmHg) are often… read more here.
Keywords: models glaucoma; retinal function; damage; exclusion criteria ... See more keywords
Neuronal and Synaptic Plasticity in the Visual Thalamus in Mouse Models of Glaucoma
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2020.626056
Abstract: Homeostatic plasticity plays important role in regulating synaptic and intrinsic neuronal function to stabilize output following perturbations to circuit activity. In glaucoma, a neurodegenerative disease of the visual system commonly associated with elevated intraocular pressure… read more here.
Keywords: models glaucoma; mouse models; neuronal synaptic; functional changes ... See more keywords
Tissue-Engineered Models for Glaucoma Research
Sign Up to like & getrecommendations! Published in 2020 at "Micromachines"
DOI: 10.3390/mi11060612
Abstract: Glaucoma is a group of optic neuropathies characterized by the progressive degeneration of retinal ganglion cells (RGCs). Patients with glaucoma generally experience elevations in intraocular pressure (IOP), followed by RGC death, peripheral vision loss and… read more here.
Keywords: glaucoma research; models glaucoma; engineered models; tissue engineered ... See more keywords