Oxytocin facilitates adaptive fear and attenuates anxiety responses in animal models and human studies—potential interaction with the corticotropin-releasing factor (CRF) system in the bed nucleus of the stria terminalis (BNST)
Sign Up to like & getrecommendations! Published in 2018 at "Cell and Tissue Research"
DOI: 10.1007/s00441-018-2889-8
Abstract: Despite its relatively well-understood role as a reproductive and pro-social peptide, oxytocin (OT) tells a more convoluted story in terms of its modulation of fear and anxiety. This nuanced story has been obscured by a… read more here.
Keywords: fear; anxiety; human studies; models human ... See more keywords
Deep learning models for human centered computing in fog and mobile edge networks
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Ambient Intelligence and Humanized Computing"
DOI: 10.1007/s12652-018-0919-8
Abstract: Deep learning is a model with multi-level layer structure that uses the underlying output as input from the top. From down to above is a process of the unsupervised learning, which automatically learns useful features,… read more here.
Keywords: human centered; models human; learning models; computing fog ... See more keywords
Tacit working models of human behavioural change I: Implementation of conservation projects
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DOI: 10.1007/s13280-019-01298-4
Abstract: The “human dimension” of conservation is increasingly recognised as critical for success. Most conservation research involving people is based not on explicit “theories of change”, but tacit local knowledge or folk theories guiding programme design.In… read more here.
Keywords: working models; change; tacit working; human behavioural ... See more keywords
Zebrafish models of human eye and inner ear diseases.
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DOI: 10.1016/bs.mcb.2016.10.006
Abstract: Eye and inner ear diseases are the most common sensory impairments that greatly impact quality of life. Zebrafish have been intensively employed to understand the fundamental mechanisms underlying eye and inner ear development. The zebrafish… read more here.
Keywords: inner ear; ear diseases; eye inner; models human ... See more keywords
Meeting Report: Can We Make Animal Models of Human Mental Illness?
Sign Up to like & getrecommendations! Published in 2018 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2018.02.010
Abstract: Modeling aspects of the human condition in animals has provided invaluable information on the physiology of all organ systems and has assisted in the development of virtually all new therapeutics. Research in cardiovascular disease, cancer,… read more here.
Keywords: meeting report; make animal; report make; models human ... See more keywords
Models of human psoriasis: Zebrafish the newly appointed player.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2019.03.018
Abstract: Psoriasis is a human chronic, immune disease with severe cutaneous and systemic manifestations. Its prevalence, among the world population, highly varies with ethnicity and geography, but not sex from remarkable low levels in Asia to… read more here.
Keywords: newly appointed; models human; psoriasis zebrafish; psoriasis ... See more keywords
Microfluidic Organ-on-a-Chip Models of Human Intestine
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2017.12.010
Abstract: Microfluidic organ-on-a-chip models of human intestine have been developed and used to study intestinal physiology and pathophysiology. In this article, we review this field and describe how microfluidic Intestine Chips offer new capabilities not possible… read more here.
Keywords: human intestine; organ chip; models human; chip models ... See more keywords
The quest for faithful in vitro models of human dendritic cells types.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.04.018
Abstract: Dendritic cells (DCs) are mononuclear phagocytes that are specialized in the induction and functional polarization of effector lymphocytes, thus orchestrating immune defenses against infections and cancer. The population of DC encompasses distinct cell types that… read more here.
Keywords: faithful vitro; human types; models human; dendritic cells ... See more keywords
Non-human primate models of human respiratory infections
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2021.04.010
Abstract: Respiratory pathogens represent a great burden for humanity and a potential source of new pandemics, as illustrated by the recent emergence of coronavirus disease 2019 (COVID-19). In recent decades, biotechnological advances have led to the… read more here.
Keywords: respiratory infections; human primate; primate models; non human ... See more keywords
Social Fear Learning: from Animal Models to Human Function
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DOI: 10.1016/j.tics.2017.04.010
Abstract: Learning about potential threats is critical for survival. Learned fear responses are acquired either through direct experiences or indirectly through social transmission. Social fear learning (SFL), also known as vicarious fear learning, is a paradigm… read more here.
Keywords: fear; fear learning; social fear; learning animal ... See more keywords
Evaluation of Commercially Available Anthelminthics in Laboratory Models of Human Intestinal Nematode Infections.
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DOI: 10.1021/acsinfecdis.0c00719
Abstract: Drug repurposing from veterinary to human medicine has been the main strategy to develop the four recommended human anthelminthics, albendazole, mebendazole, levamisole, and pyrantel pamoate, for the treatment of soil-transmitted helminthiasis. A systematic, head-to-head comparison… read more here.
Keywords: nematode infections; intestinal nematode; laboratory models; models human ... See more keywords