Development, validation and integration of in silico models to identify androgen active chemicals.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2018.12.131
Abstract: Humans are exposed to large numbers of environmental chemicals, some of which potentially interfere with the endocrine system. The identification of potential endocrine disrupting chemicals (EDCs) has gained increasing priority in the assessment of environmental… read more here.
Keywords: silico models; development validation; integration silico; identify androgen ... See more keywords
Predictive Models to Identify Small Molecule Activators and Inhibitors of Opioid Receptors
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.1c00439
Abstract: Opioid receptors (OPRs) are the main targets for the treatment of pain and related disorders. The opiate compounds that activate these receptors are effective analgesics but their use leads to adverse effects, and they often… read more here.
Keywords: activators inhibitors; small molecule; predictive models; opioid receptors ... See more keywords