Drosophila Models to Investigate Insulin Action and Mechanisms Underlying Human Diabetes Mellitus.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-0529-0_13
Abstract: Diabetes is a group of metabolic diseases in which the patient shows elevated levels of blood sugar. In healthy condition, there is the regulatory system that maintains constant glucose levels in blood. It is accomplished… read more here.
Keywords: investigate insulin; drosophila models; blood; models investigate ... See more keywords
Methods and models to investigate the physico-chemical functionality of pulmonary surfactant
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Colloid and Interface Science"
DOI: 10.1016/j.cocis.2021.101467
Abstract: Abstract The pulmonary surfactant (PS) is a complex mixture of lipids and proteins dispersed in the aqueous lining layer of the alveolar surface. Such a layer plays a key role in maintaining the proper lung… read more here.
Keywords: functionality; methods models; models investigate; pulmonary surfactant ... See more keywords
Natural and genetically-modified animal models to investigate pulmonary and extrapulmonary manifestations of COVID-19.
Sign Up to like & getrecommendations! Published in 2022 at "International reviews of immunology"
DOI: 10.1080/08830185.2022.2089666
Abstract: Coronavirus disease-19 (COVID-19), a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), is a primarily respiratory tract disease. Suitable animal models for COVID-19 are required to study various aspects of pathogenesis, drug discovery, effective… read more here.
Keywords: genetically modified; natural genetically; animal models; modified animal ... See more keywords
In vitro and in vivo models to investigate the pathomechanisms and novel treatments for pemphigoid diseases
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Dermatology"
DOI: 10.1111/exd.13415
Abstract: Pemphigoid diseases (PD) are a subgroup of rare acute or chronic autoimmune skin disorders characterized and caused by autoantibodies directed against distinct structural components of the dermal‐epidermal junction. Binding of autoantibodies to their targets leads… read more here.
Keywords: investigate pathomechanisms; vitro vivo; vivo models; models investigate ... See more keywords
Knock-In Mouse Models to Investigate the Functions of Opioid Receptors in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.807549
Abstract: Due to their low expression levels, complex multi-pass transmembrane structure, and the current lack of highly specific antibodies, the assessment of endogenous G protein-coupled receptors (GPCRs) remains challenging. While most of the research regarding their… read more here.
Keywords: knock; mouse; investigate functions; models investigate ... See more keywords
Animal models to investigate the effects of inflammation on remyelination in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.995477
Abstract: Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS). In people with MS, impaired remyelination and axonal loss lead to debilitating long-term neurologic deficits. Current MS disease-modifying… read more here.
Keywords: remyelination; animal models; models investigate; multiple sclerosis ... See more keywords