Structural Models of Ligand-Bound Sodium Channels.
Sign Up to like & getrecommendations! Published in 2018 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2017_44
Abstract: X-ray and cryo-EM structures of tetrameric and pseudo-tetrameric P-loop channels are used to elaborate homology models of mammalian voltage-gated sodium channels with drugs and neurotoxins. Such models integrate experimental data, assist in planning new experiments,… read more here.
Keywords: models ligand; structural models; sodium; bound sodium ... See more keywords
Comparative Analysis of Electrostatic Models for Ligand Docking
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2019.00052
Abstract: The precise modeling of molecular interactions remains an important goal among molecular modeling techniques. Some of the challenges in the field include the precise definition of a Hamiltonian for biomolecular systems, together with precise parameters… read more here.
Keywords: energies computed; models ligand; model; coulomb model ... See more keywords