Mitochondrial Neurodegeneration: Lessons from Drosophila melanogaster Models
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DOI: 10.3390/biom13020378
Abstract: The fruit fly—i.e., Drosophila melanogaster—has proven to be a very useful model for the understanding of basic physiological processes, such as development or ageing. The availability of straightforward genetic tools that can be used to… read more here.
Keywords: mitochondrial neurodegeneration; neurodegeneration lessons; models mitochondrial; melanogaster ... See more keywords
Neurological Phenotypes in Mouse Models of Mitochondrial Disease and Relevance to Human Neuropathology
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DOI: 10.3390/ijms24119698
Abstract: Mitochondrial diseases represent the most common inherited neurometabolic disorders, for which no effective therapy currently exists for most patients. The unmet clinical need requires a more comprehensive understanding of the disease mechanisms and the development… read more here.
Keywords: models mitochondrial; mouse models; neurological phenotypes; mitochondrial disease ... See more keywords