Proteomic profiling of the hypothalamus in two mouse models of narcolepsy
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DOI: 10.1002/pmic.201600478
Abstract: Narcolepsy is a disabling neurological disorder of sleepiness linked to the loss of neurons producing orexin neuropeptides in the hypothalamus. Two well‐characterized phenotypic mouse models of narcolepsy, loss‐of‐function (orexin‐knockout), and progressive loss of orexin (orexin/ataxin‐3)… read more here.
Keywords: models narcolepsy; orexin; mouse models; hypothalamus two ... See more keywords
Rewiring brain circuits to block cataplexy in murine models of narcolepsy
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2017.03.017
Abstract: Narcolepsy was first identified almost 130 years ago, but it was only 15 years ago that it was identified as a neurodegenerative disease linked to a loss of orexin neurons in the brain. It is… read more here.
Keywords: models narcolepsy; orexin; rewiring brain; block cataplexy ... See more keywords