Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2017 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-017-0020-4
Abstract: Neurodegenerative diseases are a spectrum of chronic, debilitating disorders characterised by the progressive degeneration and death of neurons. Mitochondrial dysfunction has been implicated in most neurodegenerative diseases, but in many instances it is unclear whether… read more here.
Keywords: models neurodegenerative; dysfunction; neurodegenerative diseases; cellular models ... See more keywords
Altered exocytosis in chromaffin cells from mouse models of neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2018 at "Acta Physiologica"
DOI: 10.1111/apha.13090
Abstract: Chromaffin cells from the adrenal gland (CCs) have extensively been used to explore the molecular structure and function of the exocytotic machinery, neurotransmitter release and synaptic transmission. The CC is integrated in the sympathoadrenal axis… read more here.
Keywords: models neurodegenerative; mouse models; chromaffin cells; exocytotic events ... See more keywords
Patient-Specific iPSCs-Based Models of Neurodegenerative Diseases: Focus on Aberrant Calcium Signaling
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020624
Abstract: The development of cell reprogramming technologies became a breakthrough in the creation of new models of human diseases, including neurodegenerative pathologies. The iPSCs-based models allow for the studying of both hereditary and sporadic cases of… read more here.
Keywords: models neurodegenerative; calcium signaling; patient specific; ipscs based ... See more keywords