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Published in 2022 at "Journal of Medical Genetics"
DOI: 10.1136/jmedgenet-2021-108315
Abstract: Primary ciliopathies are rare inherited disorders caused by structural or functional defects in the primary cilium, a subcellular organelle present on the surface of most cells. Primary ciliopathies show considerable clinical and genetic heterogeneity, with…
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Keywords:
derived cellular;
models primary;
patient derived;
primary ciliopathies ... See more keywords
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Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.953031
Abstract: Central nervous system (CNS) diseases have been a growing threat to the health of humanity, emphasizing the urgent need of exploring the pathogenesis and therapeutic approaches of various CNS diseases. Primary neurons are directly obtained…
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Keywords:
culture;
vitro models;
primary neurons;
novel vitro ... See more keywords