Articles with "models primary" as a keyword



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Patient-derived cellular models of primary ciliopathies

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Published in 2022 at "Journal of Medical Genetics"

DOI: 10.1136/jmedgenet-2021-108315

Abstract: Primary ciliopathies are rare inherited disorders caused by structural or functional defects in the primary cilium, a subcellular organelle present on the surface of most cells. Primary ciliopathies show considerable clinical and genetic heterogeneity, with… read more here.

Keywords: derived cellular; models primary; patient derived; primary ciliopathies ... See more keywords
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Recent progresses in novel in vitro models of primary neurons: A biomaterial perspective

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Published in 2022 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2022.953031

Abstract: Central nervous system (CNS) diseases have been a growing threat to the health of humanity, emphasizing the urgent need of exploring the pathogenesis and therapeutic approaches of various CNS diseases. Primary neurons are directly obtained… read more here.

Keywords: culture; vitro models; primary neurons; novel vitro ... See more keywords