Influenza vaccine combined with moderate-dose PD1 blockade reduces amyloid-β accumulation and improves cognition in APP/PS1 mice
Sign Up to like & getrecommendations! Published in 2021 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2020.09.015
Abstract: Immune dysfunction is implicated in Alzheimer's disease (AD), whereas systemic immune modulation may be neuroprotective. Our previous results have indicated immune challenge with Bacillus Calmette-Guerin attenuates AD pathology in animal models by boosting the systemic… read more here.
Keywords: influenza vaccine; ps1 mice; pathology; app ps1 ... See more keywords
Free radical scavenger edaravone produces robust neuroprotection in a rat model of spinal cord injury
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2017.12.035
Abstract: We used a multimodal approach to evaluate the effects of edaravone in a rat model of spinal cord injury (SCI). SCI was induced by extradural compression of thoracic spinal cord. In experiment 1, 30 min prior… read more here.
Keywords: dose edaravone; moderate dose; edaravone; spinal cord ... See more keywords
Randomized Controlled Trial of Fixed Low-Vs Moderate-Dose Hydroxyurea for Primary Stroke Prevention in Sub-Saharan Africa: Final Results of the Spring Trial
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-141436
Abstract: Introduction: In children with sickle cell anemia (SCA) without transcranial Doppler (TCD) screening, the incidence rates of ischemic strokes is approximately the same among children living in low- and high- low-resource settings (Pediatr Neurol. 2019;95:73-78.)… read more here.
Keywords: fixed low; trial; moderate dose; dose hydroxyurea ... See more keywords
Moderate dose serial therapy for aged and resistant patients with cholangiocarcinomas.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.e16160
Abstract: e16160 Background: Advanced (Adv) intrahepatic IH Cholangiocarcinoma BD trials found multi-drug, sequences (GFLIO) safely expand eligibility (El) for patients (pts) of all ages -/+ resistant Ca (R). Two series had response/survival (S) of 80% /… read more here.
Keywords: therapy; serial therapy; therapy aged; dose serial ... See more keywords
High-dose atorvastatin versus moderate dose on early vascular protection after ST-elevation myocardial infarction
Sign Up to like & getrecommendations! Published in 2017 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s135173
Abstract: Background and aim Clinical benefits of early high-dose statin therapy after acute coronary syndromes are widely known; however, there is poor evidence on the specific setting of ST-elevation myocardial infarction (STEMI) and dose-dependent effects of… read more here.
Keywords: dose atorvastatin; high dose; myocardial infarction; elevation myocardial ... See more keywords
Cost-Effectiveness Analysis of Ezetimibe as the Add-on Treatment to Moderate-Dose Rosuvastatin versus High-Dose Rosuvastatin in the Secondary Prevention of Cardiovascular Diseases in China: A Markov Model Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s213968
Abstract: Background For patients with inadequate control of cholesterol using moderate-dose statins in the secondary prevention of cardiovascular diseases (CVD), either doubling the dose of statins or adding ezetimibe should be considered. The cost-effectiveness of them… read more here.
Keywords: dose rosuvastatin; dose; cost effectiveness; moderate dose ... See more keywords
An Eight-year, Single-center Experience on Ultrasound Assisted Thrombolysis with Moderate-dose, Slow-infusion Regimen in Pulmonary Embolism.
Sign Up to like & getrecommendations! Published in 2022 at "Current vascular pharmacology"
DOI: 10.2174/1570161120666220428095705
Abstract: BACKGROUND There is limited data on moderate-dose with slow-infusion thrombolytic regimen by ultrasound-asssisted-thrombolysis (USAT) in patients with acute pulmonary embolism (PE). AIMS In this study, our eight-year experience on USAT with moderate-dose, slow-infusion tissue-type plasminogen… read more here.
Keywords: dose slow; mortality; infusion; moderate dose ... See more keywords
Prostate SBRT: Comparison the Efficacy and Toxicity of Two Different Dose Fractionation Schedules
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.00936
Abstract: Background: CyberKnife SBRT is capable of producing dosimetry comparable to that created by HDR brachytherapy. Our original CyberKnife prostate SBRT schedule of 3,800 cGy/4 fractions (“high dose”) was based upon favorable published prostate HDR brachytherapy… read more here.
Keywords: high dose; psa nadir; toxicity; dose ... See more keywords
Effects of High-Intensity Interval Training on Executive Functions in College Students: Evidence from Different Doses
Sign Up to like & getrecommendations! Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13040571
Abstract: Background: Different doses of high-intensity interval training (HIIT) may affect individuals’ executive functions (EF). In this study, low-dose HIIT and moderate-dose HIIT were used to explore different doses of HIIT in terms of the impact… read more here.
Keywords: hiit; time; dose group; group ... See more keywords
Revealing the Increased Stress Response Behavior through Transcriptomic Analysis of Adult Zebrafish Brain after Chronic Low to Moderate Dose Rates of Ionizing Radiation
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14153793
Abstract: Simple Summary The increasing use of radiopharmaceuticals for medical diagnostics and radiotherapy raises concerns regarding health risks for both humans and the environment. Additionally, in the context of major nuclear accidents like in Chernobyl and… read more here.
Keywords: behavior; low moderate; dose; radiation ... See more keywords