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Published in 2022 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehab820
Abstract: Abstract Aims Hypertriglyceridaemia is associated with increased risk of cardiovascular events. This clinical trial evaluated olezarsen, an N-acetyl-galactosamine-conjugated antisense oligonucleotide targeted to hepatic APOC3 mRNA to inhibit apolipoprotein C-III (apoC-III) production, in lowering triglyceride levels…
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Keywords:
every weeks;
apolipoprotein iii;
moderate hypertriglyceridaemia;
risk ... See more keywords