Xenobiotic responses of Drosophila melanogaster to insecticides with different modes of action and entry.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21958
Abstract: Depending on their chemical structure, insecticides enter the insect body either through the cuticle or by ingestion (mode of entry [MoE]), and, naturally, harm or even kill insects through different mechanisms (modes of action). In parallel,… read more here.
Keywords: modes action; entry; two moes; response ... See more keywords
Mammalian Chemical Genomics towards Identifying Targets and Elucidating Modes‐of‐Action of Bioactive Compounds
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100561
Abstract: The step of identifying target molecules and elucidating the mode of action of bioactive compounds is a major bottleneck for drug discovery from phenotypic screening. Genetic screening for genes that affect drug sensitivity or phenotypes… read more here.
Keywords: chemical; action bioactive; target molecules; action ... See more keywords
Direct and indirect approaches to identify drug modes of action
Sign Up to like & getrecommendations! Published in 2018 at "IUBMB Life"
DOI: 10.1002/iub.1697
Abstract: Phenotypic assays are becoming increasingly more common among drug discovery practices, expanding drug target diversity as lead compounds identified through such screens are not limited to known targets. While increasing diversity is beneficial to the… read more here.
Keywords: drug; modes action; drug discovery; action ... See more keywords
Potential modes of action of Pseudomonas fluorescens ZX during biocontrol of blue mold decay on postharvest citrus.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.10079
Abstract: BACKGROUND The application of chemical fungicides is currently the main method to control postharvest decay of fruits and vegetables. However, public concern has been growing towards the effect of fungicides on food safety, human health,… read more here.
Keywords: pseudomonas fluorescens; decay; microscopy; blue mold ... See more keywords
Evaluation of modes of action of pesticides to Daphnia magna based on QSAR, excess toxicity and critical body residues.
Sign Up to like & getrecommendations! Published in 2020 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.111046
Abstract: Agricultural pesticides serve as effective controls of unwanted weeds and pests. However, these same chemicals can exert toxic effects in non-target organisms. To determine chemical modes of action, the toxicity ratio (TR) and critical body… read more here.
Keywords: daphnia magna; body residues; excess toxicity; toxicity ... See more keywords
Rosmarinic acid: modes of action, medicinal values and health benefits
Sign Up to like & getrecommendations! Published in 2017 at "Animal Health Research Reviews"
DOI: 10.1017/s1466252317000081
Abstract: Abstract The supplementation of livestock rations with herbs containing bioactive components, such as rosmarinic acid (RA), have shown promising results as a natural feed additive in promoting growth, productive and reproductive performance, feed utilization, fertility,… read more here.
Keywords: rosmarinic acid; action medicinal; acid modes; modes action ... See more keywords
Dicationic Herbicidal Ionic Liquids Comprising Two Active Ingredients Exhibiting Different Modes of Action
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Agricultural and Food Chemistry"
DOI: 10.1021/acs.jafc.1c07750
Abstract: In the framework of this study, dicationic herbicidal ionic liquids (HILs) containing tetramethylene-1,4-bis(decyldimethylammonium) and dodecylmethylene-1,12-bis(decyldimethylammonium), including two different herbicidal anions exhibiting different modes of action, were synthesized and characterized. One herbicide incorporated into the HILs… read more here.
Keywords: herbicidal ionic; herbicidal; modes action; dicationic herbicidal ... See more keywords
Graphene-Borate as an Efficient Fire Retardant for Cellulosic Materials with Multiple and Synergetic Modes of Action.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b00572
Abstract: To address high fire risks of flamable cellulosic materials, that can trigger easy combustion, flame propagation, and release of toxic gases, we report a new fire-retardant approach using synergetic actions combining unique properties of reduced… read more here.
Keywords: graphene borate; fire retardant; cellulosic materials; modes action ... See more keywords
Elucidating the modes of action for bioactive compounds in a cell-specific manner by large-scale chemically-induced transcriptomics
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40164
Abstract: The identification of the modes of action of bioactive compounds is a major challenge in chemical systems biology of diseases. Genome-wide expression profiling of transcriptional responses to compound treatment for human cell lines is a… read more here.
Keywords: large scale; modes action; bioactive compounds; action ... See more keywords
Thiocyanate: a review and evaluation of the kinetics and the modes of action for thyroid hormone perturbations
Sign Up to like & getrecommendations! Published in 2017 at "Critical Reviews in Toxicology"
DOI: 10.1080/10408444.2017.1281590
Abstract: Abstract Exposure of the population to thiocyanate is predominantly through the diet and cigarette smoke. Thiocyanate is a potential thyroid disruptor due to its capacity to inhibit the uptake of iodide by the thyroid. Thiocyanate… read more here.
Keywords: thiocyanate; thyroid hormone; action; modes action ... See more keywords
Agent-based modelling of iron cycling bacteria provides a framework for testing alternative environmental conditions and modes of action
Sign Up to like & getrecommendations! Published in 2022 at "Royal Society Open Science"
DOI: 10.1098/rsos.211553
Abstract: Iron-reducing and iron-oxidizing bacteria are of interest in a variety of environmental and industrial applications. Such bacteria often co-occur at oxic-anoxic gradients in aquatic and terrestrial habitats. In this paper, we present the first computational… read more here.
Keywords: modes action; iron; agent based; environmental conditions ... See more keywords