Exploring the binding mechanism of HDAC8 selective inhibitors: Lessons from the modification of Cap group
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29583
Abstract: The abnormal expression of histone deacetylase 8 (HDAC8) has been reported to associate with various cancer entities (colon, breast cancer, pancreas, etc.) as well as parasitic diseases, making HDAC8 gradually develop into an attractive and… read more here.
Keywords: binding mechanism; hdac8; group; modification cap ... See more keywords
Chemo-Enzymatic Modification of the 5' Cap To Study mRNAs.
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.2c00059
Abstract: ConspectusThe central dogma of molecular biology hinges on messenger RNA (mRNA), which presents a blueprint of the genetic information encoded in the DNA and serves as a template for translation into proteins. In addition to… read more here.
Keywords: modification; modification cap; cap; study ... See more keywords